Re: [AMBER] How to denature DNA

From: Adrian Roitberg <roitberg.qtp.ufl.edu>
Date: Tue, 8 Sep 2009 15:04:30 +0100

Dear balaji,

You are confusing a number of issues here.
DNA can denature by a number of methods, 99% of which does not involve
pulling anything.
The usual methods involve raising the temperature, adding chemical
denaturants, etc.

Pulling DNA strands is a state of the art experimental technique, that
probably has little to do with denaturation.

Adrian


balaji nagarajan wrote:
> Dear Amber !
>
> I would like to denature the DNA,
> is it possible to pull the DNA on both the strands
> so that one can study how it denature.
>
> regards
> balaji
>
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-- 
                            Dr. Adrian E. Roitberg
                              Associate Professor
                             Quantum Theory Project
                            Department of Chemistry
                  Senior Editor. Journal of Physical Chemistry
                           American Chemical Society
University of Florida                         PHONE 352 392-6972
P.O. Box 118435                               FAX   352 392-8722
Gainesville, FL 32611-8435                    Email adrian.qtp.ufl.edu
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Received on Mon Sep 14 2009 - 13:34:44 PDT
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