Re: [AMBER] Mutate double stranded DNA?

From: Vlad Cojocaru <vlad.cojocaru.mpi-muenster.mpg.de>
Date: Thu, 13 May 2021 12:45:46 +0200

Hi Gustavo,

We are using Chimera for this (swapna function).

Cheers
Vlad

On 13/05/2021 10:59, Carlos Simmerling wrote:
> Hi Gustavo,
> I have an old Fortran code that does this. I'll send it off list, replying
> here for the archive.
> Carlos
>
> On Wed, May 12, 2021, 9:02 PM Gustavo Seabra <gustavo.seabra.gmail.com>
> wrote:
>
>> Friends,
>>
>> I'm looking for a tool that allows me to, starting from a PDB file with a
>> double-strand DNA on it, mutate some nucleic acids but keeping the original
>> backbone. Extra points if it can automatically apply the complementary
>> mutations on the second strand.
>>
>> Does anyone know of such a tool?
>>
>> Thanks!
>>
>> --
>> Gustavo Seabra
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>>
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-- 
Vlad Cojocaru, PD (Habil.), Ph.D.
-----------------------------------------------
Project Group Leader
Department of Cell and Developmental Biology
Max Planck Institute for Molecular Biomedicine
Röntgenstrasse 20, 48149 Münster, Germany
-----------------------------------------------
Tel: +49-251-70365-324; Fax: +49-251-70365-399
Email: vlad.cojocaru[at]mpi-muenster.mpg.de
http://www.mpi-muenster.mpg.de/43241/cojocaru
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Received on Thu May 13 2021 - 04:00:02 PDT
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