Dear Gustavo,
Before the experts chime in: Have you considered PyMOL? There is a
function to perform mutations:
https://pymolwiki.org/index.php/Mutagenesis
It can also be quite easily turned into a python script, where you could
make sure the complementary mutations are performed as well.
Best,
Mariano
On 13/05/2021 3:01, Gustavo Seabra wrote:
> Friends,
>
> I'm looking for a tool that allows me to, starting from a PDB file with a double-strand DNA on it, mutate some nucleic acids but keeping the original backbone. Extra points if it can automatically apply the complementary mutations on the second strand.
>
> Does anyone know of such a tool?
>
> Thanks!
>
> --
> Gustavo Seabra
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Received on Thu May 13 2021 - 00:30:02 PDT
