Re: [AMBER] Mutate double stranded DNA?

From: Mariano Curti <mcurti.iciq.es>
Date: Thu, 13 May 2021 09:29:18 +0200

Dear Gustavo,

Before the experts chime in: Have you considered PyMOL? There is a
function to perform mutations:

https://pymolwiki.org/index.php/Mutagenesis

It can also be quite easily turned into a python script, where you could
make sure the complementary mutations are performed as well.

Best,

Mariano



On 13/05/2021 3:01, Gustavo Seabra wrote:
> Friends,
>
> I'm looking for a tool that allows me to, starting from a PDB file with a double-strand DNA on it, mutate some nucleic acids but keeping the original backbone. Extra points if it can automatically apply the complementary mutations on the second strand.
>
> Does anyone know of such a tool?
>
> Thanks!
>
> --
> Gustavo Seabra
> _______________________________________________
> AMBER mailing list
> AMBER.ambermd.org
> http://lists.ambermd.org/mailman/listinfo/amber


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