On Sat, Apr 10, 2021, A R wrote:
>
>Could you please an additional answer, if the ligand is covalently bonded
>with a cofactor such as FAD. Can i use ligand-FAD conjugate as a ligand
>coordinates input file in tleap. Next prepare complex between protein and
>ligand-FDA conjugate and proceed in similar way to simple md simulation
>process of non covalent bonded protein-ligand complex.
The above sounds correct to me: the ligand-FAD conjugate is just another
type of ligand, and the conjugate is not covalently bound to the protein.
...good luck...dac
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Received on Sun Apr 11 2021 - 06:30:03 PDT
