Hi,
For the methodology used to build nucleic acid models through 3D-NuS (
http://iith.ac.in/3dnus/), please refer:
3D-NuS: A Web Server for Automated Modeling and Visualization of
Non-Canonical 3-Dimensional Nucleic Acid Structures.
<
https://www.ncbi.nlm.nih.gov/pubmed/28652006>
Patro LPP, Kumar A, Kolimi N, *Rathinavelan* T.
J Mol Biol. 2017 Jun 23. pii: S0022-2836(17)30314-5. doi:
10.1016/j.jmb.2017.06.013.
*Thanks & Regards,*
*Yogeeshwar Ajjugal*
*Ph.D ScholarC/O Dr.Thenmalarchelvi Rathinavelan*
*Dept Of Biotechnology,Indian Institute of Technology Hyderabad,*
*Kandi, Medak-502285.*
On Fri, Jul 28, 2017 at 11:42 AM, Yogeeshwar Ajjugal <
bo14resch11004.iith.ac.in> wrote:
> Hi,
> 3D-NuS (http://iith.ac.in/3dnus/) has the facility of creating steric
> free and energy minimized DNA structures with mutated/mismatch base pairs.
> It also facilitates modeling non-canonical nucleic acid structures like
> RNA/DNA duplexes with mis-match base pairs, DNA/RNA chimeras, triplexes and
> G-quadruplexes.
>
> Regards.
> Yoogi
>
> *Thanks & Regards,*
>
> *Yogeeshwar Ajjugal*
>
> *Ph.D ScholarC/O Dr.Thenmalarchelvi Rathinavelan*
>
>
> *Dept Of Biotechnology,Indian Institute of Technology Hyderabad,*
> *Kandi, Medak-502285.*
>
> On Thu, Jul 27, 2017 at 5:42 PM, Debostuti Ghoshdastidar <
> debostutighosh.gmail.com> wrote:
>
>> Dear Amber Users
>>
>> I have an existing DNA/protein pdb and need to mutate the DNA at multiple
>> base pairs. Is it possible to do so using the NAB utility? Alternatively,
>> can I add nucleic acid bases to an existing DNA structure?
>>
>> Any suggestions would be helpful.
>>
>> Thank you
>>
>> --
>> Debostuti Ghosh Dastidar
>> DST SERB National Post-Doctoral Fellow
>> Molecular Biophysics Unit
>> Indian Institute of Science, Bangalore
>> _______________________________________________
>> AMBER mailing list
>> AMBER.ambermd.org
>> http://lists.ambermd.org/mailman/listinfo/amber
>>
>
>
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Received on Fri Jul 28 2017 - 00:00:03 PDT
