Hi,
3D-NuS (
http://iith.ac.in/3dnus/) has the facility of creating steric
free and energy minimized DNA structures with mutated/mismatch base pairs.
It also facilitates modeling non-canonical nucleic acid structures like
RNA/DNA duplexes with mis-match base pairs, DNA/RNA chimeras, triplexes and
G-quadruplexes.
Regards.
Yoogi
*Thanks & Regards,*
*Yogeeshwar Ajjugal*
*Ph.D ScholarC/O Dr.Thenmalarchelvi Rathinavelan*
*Dept Of Biotechnology,Indian Institute of Technology Hyderabad,*
*Kandi, Medak-502285.*
On Thu, Jul 27, 2017 at 5:42 PM, Debostuti Ghoshdastidar <
debostutighosh.gmail.com> wrote:
> Dear Amber Users
>
> I have an existing DNA/protein pdb and need to mutate the DNA at multiple
> base pairs. Is it possible to do so using the NAB utility? Alternatively,
> can I add nucleic acid bases to an existing DNA structure?
>
> Any suggestions would be helpful.
>
> Thank you
>
> --
> Debostuti Ghosh Dastidar
> DST SERB National Post-Doctoral Fellow
> Molecular Biophysics Unit
> Indian Institute of Science, Bangalore
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Received on Thu Jul 27 2017 - 23:30:03 PDT
