[AMBER] Question regarding protein-Dna binding free energy

From: Mahdieh Hadi <mahdieh.hadi.bric.ku.dk>
Date: Thu, 25 Feb 2016 14:25:54 +0000

Hi,
I have prepared pdb, inpcrd and prompt files for my DNA, and I have pdb file of my protein. But I do not have the complex of them. I am going to predict the mutations in my DNA sequence that will decrease the binding affinity to the protein to the least level.
Would you please give me an overview of what should I do? How should I prepare DNA-Protein complex and etc?
Bests
Mahdieh
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Received on Thu Feb 25 2016 - 06:30:07 PST
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