Re: [AMBER] Hoogsteen-Watson Base pair

From: David A Case <david.case.rutgers.edu>
Date: Wed, 23 Sep 2015 15:21:33 -0400

On Wed, Sep 23, 2015, Martina Devi wrote:
>
> I would like to know how to build a base-pair where one base has
> watson-crick edge and the other has hoogsten edge.Though I build a base
> pair through NAB and it is working fine through the given input:
>
> molecule m;
> m = fd_helix( "arna", "ccc", "rna");
> putpdb( "a-rna.nab.pdb", m, "-wwpdb");
>
> The above input give a base pair where all the pairs has watson-crick edge.
> So is there any input for generating hoogsten edge.

There is no high-level user interface for this. But Section 36.12.3
describes in detail how watson-crick pairs are constructed, so you can have
a try at modifying this to make watson-crick/hoogsteen pairs.

...good luck....dac


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Received on Wed Sep 23 2015 - 12:30:04 PDT
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