Re: [AMBER] single strand DNA in hairpin conformation

From: Urszula Uciechowska <urszula.uciechowska.biotech.ug.edu.pl>
Date: Wed, 18 Feb 2015 17:55:42 +0100

 Where can I find the pseudoknot example in order to adopt it to hairpin.
I checked CYANA but we do not have a license for this software.

Thank you in advance for any suggestions.

best regards
Urszula

> On Thu, Feb 12, 2015, Urszula Uciechowska wrote:
>>
>> I was wondering if its possible to build a ssDNA in hairpin conformation
>> using nab? Does anyone know other software where I could do this?
>
> It is certainly *possible*: the pseudoknot example could be adapted to a
> hairpin. It uses distance geometry to construct conformations satisfying
> certain restraints, such as WC pairing in the stem.
>
> Having said that, there are lots of other solutions, and a Google search
> will
> point to many of them. I personally would use CYANA for this purpose, but
> that is largely because I'm familiar with that code. You could also set
> up
> constraints in sander and "fold" the dna from an extended configuration.
>
> Maybe others on the list will have more specific suggestions.
>
> ....dac
>
>
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University of Gdansk and Medical Univesity of Gdansk
Department of Molecular and Cellular Biology
ul. Kladki 24
80-822 Gdansk
Poland


-----------------------------------------
Ta wiadomość została wysłana z serwera Uniwersytetu Gdańskiego
http://www.ug.edu.pl/


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Received on Wed Feb 18 2015 - 09:00:03 PST
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