Re: AMBER: testing protein stability

From: Sally Pias <>
Date: Fri, 22 Jun 2007 15:57:27 -0600

On 6/22/07, Carlos Simmerling <> wrote:
> you might be better off doing free energy calculations where you mutate the
> residue
> in the protein and again in a peptide model for the unfolded state, and use
> that to
> estimate the effect on stability.

Do you know of any examples of this type of study in the literature?


Sally Pias
The AMBER Mail Reflector
To post, send mail to
To unsubscribe, send "unsubscribe amber" to
Received on Sun Jun 24 2007 - 06:07:49 PDT
Custom Search