Hi Lod,
This might simply mean adding an ACE residue at the N-terminal of your
protein. This is usually done when the available structure has missing
residues on the terminal ends. To avoid a positive charge on the N-terminal
end of your truncated protein, you can cap it using ACE. The same thing can
also be done for a truncated C-terminal end using NME (N-methylation).
On Fri, Apr 10, 2020 at 11:48 AM Lod King <lodking407.gmail.com> wrote:
> Hi Amber
>
> *I have seen many papers talking about *"acetylated the truncated N-
> terminal ....... to eliminate artificial charges at the N-termini"
>
> *I wonder what does it mean to the PDB structure and how did it achieve? *
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Received on Thu Apr 09 2020 - 22:30:03 PDT
