Dear users,
I am studying an RNA hairpin which retains its structure at 25 deg C, but
melts at physiological temperature (37 deg C).
available literature on RNA unfolding either deals with force-induced
unfolding or high temperature MD or REMD.
Is there any way i can simulate the unfolding pathway/dynamics of this
structure in Amber..as far i know, setting up REMD for this small
temperature scale won't make sense.
Thank you
Asmita
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Received on Wed May 27 2015 - 04:00:04 PDT
