On Fri, Oct 24, 2014 at 8:46 AM, Asfa Ali <asfa.iisc.gmail.com> wrote:
> Sir,
>
> When I did the simulations with:
> tleap -s -f leaprc.ff99bsc0
> loadoff RNA_CI.lib
> source leaprc.gaff
> ...
> I did not notice any perturbation in the RNA structure. So is it necessary
> to repeat the calculations using ff14SB?
>
Well if any of the people that have responded to this thread already were
to review your paper, I think they made it pretty clear that they would
reject work that uses ff99bsc0 for RNA rather than some of the much better,
newer force fields.
All the best,
Jason
--
Jason M. Swails
BioMaPS,
Rutgers University
Postdoctoral Researcher
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Received on Fri Oct 24 2014 - 06:30:02 PDT
