[AMBER] RMSD of globular proteins

From: Anselm Horn <Anselm.Horn.biochem.uni-erlangen.de>
Date: Fri, 25 Jan 2013 00:05:13 +0100

Dear all,

the RMSD value of protein backbone movements is an often-used measure
for the similarity to the initial structure. A value of ca. 2 Angstroem
is thereby generally thought to indicate a stable simulation, as this
value is obtained for simulations of globular proteins.

My question now is: Is anybody aware of published work, where the
foundation of this (or a similar) value has been obtained by some
analysis or theoretical consideration? Or is this (globular protein =
2.0 A) just common knowledge/experience?

Thanks in advance!

Anselm


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Received on Thu Jan 24 2013 - 15:30:02 PST
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