Hi all,
I was wondering what advantages a polarizable forcefield offers over a fixed charge forcefield. I have been using AMBER99SB for modeling but I have been considering switching over to a polarizable forcefield if these do a better job at modeling protein surface interactions. The specific protein I am looking at has a high density of polar side chains along the surface so I was wondering if switching forcefields would give me additional accuracy.
Thank you,
Nikolay Rodionov
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Received on Fri Jul 06 2012 - 07:30:03 PDT
