Dear Acoot,
You can try propka server to predict it.
Rajendras
On Fri, Apr 6, 2012 at 4:55 PM, Acoot Brett <acootbrett.yahoo.com> wrote:
> Dear All,
>
>
> For low resolution structure PDB, the protonation state of histidine is
> not clear. Then should we correct our PDB file manually so that leap can
> get the correct imput filesd? Or leap treat the protonation state of HIS
> automatically?
>
> Even for high resolution structure of protein, the protonation state of
> HIS is usallly unclear or unspefified. Do we have some rules to correct the
> protonation state of the residues including HIS? Or there is a server for
> this purpose?
>
>
> Cheers,
>
> Acoot
> _______________________________________________
> AMBER mailing list
> AMBER.ambermd.org
> http://lists.ambermd.org/mailman/listinfo/amber
>
--
Rajendra Sharma
Junior Research Fellow,
Computational Biophysics,
*National Center for Biological Sciences,*
(Tata institute of Fundamental Research)
India.
Mobile No. +91-9950675288
_______________________________________________
AMBER mailing list
AMBER.ambermd.org
http://lists.ambermd.org/mailman/listinfo/amber
Received on Fri Apr 06 2012 - 06:30:21 PDT
