> Have a nice day, I am looking for protocol or method for parametrization of
> a new ligand. Is there any way I can parametrize it without the use of
> Gaussian?
You could use GAMESS-US or Firefly instead of Gaussian.
You could also use R.E.D. Server http://q4md-forcefieldtools.org/REDS/
which provides the cluster, the QM program (Gaussian, GAMESS or
Firefly) & the last version of R.E.D.
