AMBER: Amber DNA Model for X-ray Crystallography

From: Hopkins, Robert <hopkins.uhcl.edu>
Date: Fri, 11 Jan 2008 17:32:00 -0600

Dear Amber Users,

 

Is anyone aware of an example where a generic polynucleotide (say, from
nucgen)

was refined using Amber MD and then applied successfully as a search
model

for the Molecular Replacement method in order to solve a single crystal
X-ray

diffraction structure, even as a test of Amber?

 

I'd greatly appreciate any information on such an approach. Thanks!

 

Bob Hopkins


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Received on Sun Jan 13 2008 - 06:07:30 PST
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