Determining if the pthread_create exist failed with the following output: Change Dir: /usr/AMBER-Files/amber20_src/build/CMakeFiles/CMakeTmp Run Build Command:"/usr/bin/make" "cmTC_fd407/fast" /usr/bin/make -f CMakeFiles/cmTC_fd407.dir/build.make CMakeFiles/cmTC_fd407.dir/build make[1]: Entering directory '/usr/AMBER-Files/amber20_src/build/CMakeFiles/CMakeTmp' Building C object CMakeFiles/cmTC_fd407.dir/CheckSymbolExists.c.o /usr/bin/gcc -fPIC -std=gnu99 -o CMakeFiles/cmTC_fd407.dir/CheckSymbolExists.c.o -c /usr/AMBER-Files/amber20_src/build/CMakeFiles/CMakeTmp/CheckSymbolExists.c Linking C executable cmTC_fd407 /usr/bin/cmake -E cmake_link_script CMakeFiles/cmTC_fd407.dir/link.txt --verbose=1 /usr/bin/gcc -fPIC CMakeFiles/cmTC_fd407.dir/CheckSymbolExists.c.o -o cmTC_fd407 CMakeFiles/cmTC_fd407.dir/CheckSymbolExists.c.o: In function `main': CheckSymbolExists.c:(.text+0x1b): undefined reference to `pthread_create' collect2: error: ld returned 1 exit status CMakeFiles/cmTC_fd407.dir/build.make:97: recipe for target 'cmTC_fd407' failed make[1]: *** [cmTC_fd407] Error 1 make[1]: Leaving directory '/usr/AMBER-Files/amber20_src/build/CMakeFiles/CMakeTmp' Makefile:126: recipe for target 'cmTC_fd407/fast' failed make: *** [cmTC_fd407/fast] Error 2 File /usr/AMBER-Files/amber20_src/build/CMakeFiles/CMakeTmp/CheckSymbolExists.c: /* */ #include int main(int argc, char** argv) { (void)argv; #ifndef pthread_create return ((int*)(&pthread_create))[argc]; #else (void)argc; return 0; #endif } Determining if the function pthread_create exists in the pthreads failed with the following output: Change Dir: /usr/AMBER-Files/amber20_src/build/CMakeFiles/CMakeTmp Run Build Command:"/usr/bin/make" "cmTC_9df28/fast" /usr/bin/make -f CMakeFiles/cmTC_9df28.dir/build.make CMakeFiles/cmTC_9df28.dir/build make[1]: Entering directory '/usr/AMBER-Files/amber20_src/build/CMakeFiles/CMakeTmp' Building C object CMakeFiles/cmTC_9df28.dir/CheckFunctionExists.c.o /usr/bin/gcc -fPIC -DCHECK_FUNCTION_EXISTS=pthread_create -std=gnu99 -o CMakeFiles/cmTC_9df28.dir/CheckFunctionExists.c.o -c /usr/share/cmake-3.10/Modules/CheckFunctionExists.c Linking C executable cmTC_9df28 /usr/bin/cmake -E cmake_link_script CMakeFiles/cmTC_9df28.dir/link.txt --verbose=1 /usr/bin/gcc -fPIC -DCHECK_FUNCTION_EXISTS=pthread_create CMakeFiles/cmTC_9df28.dir/CheckFunctionExists.c.o -o cmTC_9df28 -lpthreads /usr/bin/ld: cannot find -lpthreads collect2: error: ld returned 1 exit status CMakeFiles/cmTC_9df28.dir/build.make:97: recipe for target 'cmTC_9df28' failed make[1]: *** [cmTC_9df28] Error 1 make[1]: Leaving directory '/usr/AMBER-Files/amber20_src/build/CMakeFiles/CMakeTmp' Makefile:126: recipe for target 'cmTC_9df28/fast' failed make: *** [cmTC_9df28/fast] Error 2