Dear Sir,
I used mm-pbsa to calculate the binding free energy of a protein-DNA complex,
Is the PBTOT given as the out put of this is the relative binding free energy?
If I want to calculate the absolute free energy ( in order to compare it with the experimental value) should I subtract
T∆ S (calculated using normal mode analysis) from PBTOT ?
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Received on Wed Jun 04 2014 - 00:30:03 PDT
