HID and HIE are the basic conditions, and HIP is the acidic one. It would
require EXTREME conditions to remove another hydrogen from the ring.
On Wed, Mar 27, 2013 at 11:18 PM, Changqing Yan <ycqchemical.gmail.com>wrote:
> Dear,
>
> Since there are only HID, HIE and HIP in leap and all of them are
> protonated forms, what should I do if I want to run MD of a protein which
> contains histidine residues in basic condition?
>
> Thx and rgds,
> C.Q.
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--
Aron Broom M.Sc
PhD Student
Department of Chemistry
University of Waterloo
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Received on Wed Mar 27 2013 - 21:00:02 PDT
