[AMBER] Query regarding PNA-DNA duplex parameterization in AMBER

From: Souvik Sur <souviksur.hotmail.com>
Date: Sat, 9 Feb 2013 12:56:19 +0530

Dear Users,

I am working in amber with PNA-DNA duplex using amber10, PNA=Peptide Nucleic acid. For that first of all, I have to make initial topology files using antechamber module, usually DNA-bases(A/T/G/C) are recognized by amber but is there any compaitible parameters available for PNA in amber which recognize my PNA-base containing an entirely different backbone as compared to DNA backbone or I have to make library of my PNA-bases first, Please suggest me regarding it.

regards,
Souvik Sur
Ph. D. Student
Department Of Chemistry
University Of Delhi
India
                                               
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Received on Fri Feb 08 2013 - 23:30:02 PST
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