> For example, as it mentioned here:
> http://enzyme.fbb.msu.ru/Tutorials/Tutorial_3/
> where "constant /k/=150 pN/A allows 0.5 A thermal fluctuations of the
> constrained coordinate".
Hello, this remark just demonstrates that the distance restraint is
rather soft. But it can be sufficient to drive the
dissociation/assotiation of protein-ligand complex.
--
Dmitry Nilov
Faculty of Bioengineering and Bioinformatics,
Lomonosov Moscow State University
web: http://enzyme.fbb.msu.ru/
_______________________________________________
AMBER mailing list
AMBER.ambermd.org
http://lists.ambermd.org/mailman/listinfo/amber
Received on Tue Jul 26 2011 - 08:30:03 PDT
