how to validate ff parameters obtained from antechamber

From: Jiyoung Heo <>
Date: Thu, 27 Feb 2003 21:27:54 -0800

Dear amber users,

I generated the force field parameters for non-natural DNA bases using
antechamber. They have just some modification, so the common FF
parameters were taken from natural DNA base parameters and non-available
ones in parm98.dat were from the antechamber output.
I am wondering how you validate the force field parameters obtained by
Do you usually calculate base pairing energy and compare the QM result?
What is the best and reliable way?

Received on Fri Feb 28 2003 - 05:53:00 PST
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