parameterization of a new class of compounds (nucleic acid base analogues)

From: Vlad Cojocaru <>
Date: Mon 09 Sep 2002 11:40:05 +0200

Dear Amber users,
   I have parameterized 5 base analogues for incorporation into RNA. I
am wondering if there is way to verufy how optimal the parameterization
is. For that I need the advice of somebody who previously parameterized
base analogues like 2 amino purine for instance. I would klike to know
how did you test the new parameters?
  I would also like to know the procedure for depositing the parameters
into the Amber data base.
   Thanks a lot in advance for any answers.
  Best regards,

Vlad Cojocaru 
Max Planck Institut for Biophysical Chemistry 
Deparment: 060 
Am Fassberg 11, 37077 Goettingen, Germany 
tel: ++49-551-201.1389 
Received on Mon Sep 09 2002 - 02:40:05 PDT
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